Aberrant Regeneration of the Third Nerve

HC Chua, CB Tan, H Tjia
Correspondence: Dr Chua Hoe Chin, hoe_chin_chua@notes.ttsh.gov.sg

ABSTRACT
We describe three patients with aberrant regeneration of the third nerve secondary to traumatic brain injury. The full blown features of the syndrome include horizontal gaze-eyelid synkinesis, pseudo-Graefe sign, limitation of elevation and depression of the eye with retraction of the globe on attempted vertical movements, adduction of the involved eye on attempted elevation or depression, pseudo-Argyll Robertson pupil and absent vertical optokinetic response. The 'misdirection' incidence in our study is 15%.

Keywords: aberrant regeneration, third nerve, trauma, pseudo-Argyll Robertson
Singapore Med J 2000; 41(9): 458-459