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Accidental provocation of phaeochromocytoma: the forgotten hazard of metoclopramide?

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Singapore Med J 2005; 46(10): 557-560
Accidental provocation of phaeochromocytoma: the forgotten hazard of metoclopramide?

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MK Leow, KC Loh
Correspondence: Dr Melvin Leow, mleowsj@massmed.org

ABSTRACT
The perilous potential of metoclopramide when used inadvertently in patients harbouring phaeochromocytomas goes largely under-recognised. Despite the rarity of phaeochromocytoma, clinicians should exercise caution in the use of metoclopramide among hypertensives and those with labile blood pressures, given the potentially life-threatening crisis it can readily evoke in those with this tumour. We report a series of three patients with phaeochromocytoma who developed acute crises from metoclopramide.

Keywords: catecholamines, dopamine antagonists, hypertensive emergency, metoclopramide, phaeochromocytoma
Singapore Med J 2005; 46(10): 557-560

http://smj.org.sg/sites/default/files/4610/4610cr1.pdf
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