Skip to main content
  • Home
  • Articles
    • Archive from 2022 July
    • Archive 1960 to 2022 June
    • Accepted Articles
    • Published Ahead-of-Print
    • Supplement
  • About
  • For Authors
  • Podcasts

Carotidynia after anticancer chemotherapy

< Back to Listing

Share this Article

Singapore Med J 2014; 55(9): e142-e144; http://dx.doi.org/10.11622/smedj.2014127
Carotidynia after anticancer chemotherapy

  • Abstract
  • PDF
  • References

Hayashi S, Maruoka S, Takahashi N, Hashimoto S
Correspondence: Dr Shinichi Hayashi, shayashi@med.nihon-u.ac.jp

ABSTRACT
Carotidynia is characterised by inflammation limited to the common carotid artery, which has been recognised as a distinct disease entity by advanced vascular imaging. Although most cases of carotidynia are idiopathic, we herein present a case of carotidynia after anticancer chemotherapy. A 64-year-old male patient received docetaxel followed by granulocyte-colony stimulating factor (G-CSF) for the treatment of lung squamous carcinoma. After the treatment, bilateral cervical pain developed. Vascular imaging, including magnetic resonance imaging, computed tomography and ultrasonography, showed characteristics specific for carotidynia. Although there was no strong confirmation using tests such as a challenge test, our observations suggest that docetaxel or G-CSF could be a causative drug triggering carotidynia.

Keywords: adverse drug reactions, carotidynia, docetaxel, granulocyte-colony stimulating factor
Singapore Med J 2014; 55(9): e142-e144; http://dx.doi.org/10.11622/smedj.2014127

http://smj.org.sg/sites/default/files/5509/5509cr2.pdf

REFERENCES

1. Fay T. Atypical neuralgia. Arch Neurol Psychiatry 1927; 18:309-15.
 
2. Roseman DM. Carotidynia. A distinct syndrome. Arch Otolaryngol 1967; 85:81-4.
http://dx.doi.org/10.1001/archotol.1967.00760040083016
 
3. Classification and diagnostic criteria for headache disorders, cranial neuralgias and facial pain. Headache Classification Committee of the International Headache Society. Cephalalgia 1988; 8 Suppl 7:1-96.
 
4. Biousse V, Bousser MG. The myth of carotidynia. Neurology 1994; 44:993?5.
http://dx.doi.org/10.1212/WNL.44.6.993
 
5. Headache Classification Subcommittee of the International Headache Society. The International Classification of Headache Disorders: 2nd edition. Cephalalgia 2004; 24 Suppl 1:9-160.
 
6. Stanbro M, Gray BH, Kellicut DC. Carotidynia: revisiting an unfamiliar entity. Ann Vasc Surg 2011; 25:1144-53.
http://dx.doi.org/10.1016/j.avsg.2011.06.006
 
7. Buetow MP, Delano MC. Carotidynia. AJR Am J Roentgenol 2001; 177:947.
http://dx.doi.org/10.2214/ajr.177.4.1770947
 
8. Schaumberg J, Eckert B, Michels P. Carotidynia: magnetic resonance imaging and ultrasonographic imaging of a self-limiting disease. Clin Neurardio 2011; 21:91-4.
http://dx.doi.org/10.1007/s00062-010-0042-5
 
9. Bendix N, Glodny B, Bernathova M, Bodner G. Sonography and CT of vasculitis during gemcitabine therapy. AJC Am J Roentgenol 2005; 184(3 Suppl):S14-5.
http://dx.doi.org/10.2214/ajr.184.3_supplement.01840s14
 
10. Azar L, Fischer HD. Perivascular carotid inflammation: an unusual case of carotidynia. Rheumatol Int 2012; 32:457-9.
http://dx.doi.org/10.1007/s00296-009-1309-5
 
11. Jabre MG, Shahidi GA, Bejjani BP. Probable fluoxetine-induced carotidynia. Lancet 2009; 374:1061-2.
http://dx.doi.org/10.1016/S0140-6736(09)61694-9
 
12. Naranjo CA, Busto U, Sellers EM, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981; 30:239?45.
http://dx.doi.org/10.1038/clpt.1981.154
 
13. Ramsay LB, Stany MP, Edison JD, et al. Gemcitabine-associated large vessel vasculitis presenting as fever of unknown origins. J Clin Rheumatol 2010; 16:181-2.
http://dx.doi.org/10.1097/RHU.0b013e3181df91ad
 
14. Dasanu CA. Gemcitabine: vascular toxicity and prothrombotic potential. Expert Opin Drug Saf 2008; 7:703-16.
http://dx.doi.org/10.1517/14740330802374262
 
15. Upton PD, Smith JG, Charnock DR. Histologic confirmation of carotidynia. Otolaryngol Head Neck Surg 2003; 129:443-4.
http://dx.doi.org/10.1016/S0194-5998(03)00611-9
 
16. Adiga GU, Elkadi D, Malik SK, Fitzpatrick JD, Madajewicz S. Abdominal aortitis after use of granulocyte colony-stimulating factor. Clin Drug Investig 2009; 29:821-5.
http://dx.doi.org/10.2165/11530790-000000000-00000
×

Around the Site

Home

About SMJ

For Reviewers

Sign Up for Alerts

Issues

Current Issue

All Issues

Online First

Supplement

CME

For Authors

Instructions for Authors

Submit Manuscript


Follow us on:
        

More Links

Contact Us

Copyright

Advertise

SMJ Forms

Privacy Policy

SMA Home

Copyright 2021. Singapore Medical Association. All Rights Reserved.