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Cystic lymphoid hyperplasia of the parotid gland as the initial manifestation of HIV infection

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Singapore Med J 2014; 55(1): e12-e16; http://dx.doi.org/10.11622/smedj.2014010
Cystic lymphoid hyperplasia of the parotid gland as the initial manifestation of HIV infection

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Wu B, Ngo R, Petersson F
Correspondence: Dr Fredrik Petersson, fredrikpetersson@live.se


ABSTRACT
We report the case of a patient who presented with cystic lymphoid hyperplasia of the right parotid gland as the index diagnosis of HIV infection. Histological examination of the excised parotid gland revealed a solid-cystic lymphoepithelial lesion with a non-keratinous squamous epithelium, which grew into the lymphoid component via anastomosing cords and islands. These anastomosing cords and islands contained variably abundant B cells, several subepithelial multinucleated histiocytes, salivary ducts infiltrated by small lymphocytes, and a dense lymphoid infiltrate containing lymphoid follicles with enlarged, irregular germinal centres.

Keywords: 
AIDS, HIV-associated salivary gland disease, human immunodeficiency virus, lymphoepithelial sialadenitis, Sj?gren’s syndrome
Singapore Med J 2014; 55(1): e12-e16; http://dx.doi.org/10.11622/smedj.2014010

http://smj.org.sg/sites/default/files/5501/5501cr5.pdf

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