Exogenously-induced apparent hypermineralocorticoidism associated with ingestion of "asam boi"

Hamidon BB, Jeyabalan V
Correspondence: Dr Hamidon bin Basri, hamidon@mail.hukm.ukm.my

ABSTRACT
A 31-year-old woman presented with a one-week history of headache, generalised lethargy, weakness and poor appetite. Clinical examination showed that her blood pressure was 200/120 mmHg. On an earlier occasion, her blood pressure was found to be normal by a general practitioner whom she last visited three months earlier when she had an upper respiratory tract infection. Investigations showed hypokalaemia, suppressed serum renin and aldosterone. Further history was taken and revealed that she had been craving for guava fruits which she ate with flavoured "asam boi" (containing glycyrrhizic acid) at least three spoonfuls twice a day for the past six weeks. The hypertension and hypokalaemia resolved after two weeks of stopping the "asam boi". Her clinical picture was compatible with exogenously-induced hypermineralocortoidism.

Keywords: asam boi, exogenously-induced hypermineralocorticoidism, glycyrrhizic acid, hypermineralocorticoidism
Singapore Med J 2006; 47(2): 156-158