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The imminent threat of multidrug-resistant tuberculosis in Singapore

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Singapore Med J 2012; 53(4): 238-240
The imminent threat of multidrug-resistant tuberculosis in Singapore

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Chee CBE, KhinMar KW, Cutter J, Wang YT
Correspondence: Cynthia BE Chee, cynthia_chee@ttsh.com.sg

ABSTRACT
The global emergence of multidrug-resistant (MDR) tuberculosis (TB) and extensively drugresistant (XDR)-TB threatens to derail the efforts of TB control programmes worldwide. From 2000 to 2010, 161 pulmonary MDR-TB cases (including six XDR-TB cases) were reported in Singapore, and of these, 80% occurred among the foreign-born, with an increasing trend seen after 2004. Among new pulmonary TB cases, the highest incidence of MDR-TB occurred among patients from Myanmar (8%), followed by Vietnam (4.4%) and China (2.3%), while among those previously treated, the highest incidence was found in patients from Vietnam (50%), followed by Indonesia (33%) and Bangladesh (33%). Although the proportion of Singapore-born pulmonary TB cases with MDR-TB has remained comparatively low (0.2% and 1.3% in new and previously treated cases, respectively), there is no room for complacency. Top priority must be accorded toward the proper treatment of drug-susceptible TB cases under strict programme conditions so as to prevent the development of MDR-TB in the first place.

Keywords: extensively drug-resistant-TB, foreign-born, multidrug-resistant-TB,  Singapore, TB programme 
Singapore Med J 2012; 53(4): 238-240

http://smj.org.sg/sites/default/files/5304/5304c2.pdf
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