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Vasanwala FF, Puvanendran R, Ng JM, Suhail SM
Correspondence: Dr Farhad Fakhrudin Vasanwala, firstname.lastname@example.org
We report two cases of dengue haemorrhagic fever which developed self-limiting gross nephrotic-range proteinuria. One patient was a 32-year-old Bangladeshi and the other a 42-year-old Chinese national. Both patients did not have manifestations of renal damage, such as increase in serum creatinine, haematuria or urinary casts. Gross nephrotic-range proteinuria, which was self-limiting due to dengue haemorrhagic fever, has not been previously reported in Singapore. We postulate that this nephrotic-range proteinuria is a manifestation of increased glomerular leakage of protein, due to glomerulonephritis associated with dengue haemorrhagic fever.
Keywords: dengue haemorrhagic fever, immune complexes, nephrotic-range proteinuria, plasma leakage, self-limiting glomerulonephritis
Singapore Med J 2009; 50(7): e253-e255