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Alexis Carrel (1873-1944): Pioneer of vascular surgery and organ transplantation

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Singapore Med J 2013; 54(11): 602-603; http://dx.doi.org/10.11622/smedj.2013217
Alexis Carrel (1873-1944): Pioneer of vascular surgery and organ transplantation

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Merchant J, Tan SY
Correspondence: Prof Tan Siang Yong, siang@hawaii.edu

SUMMARY
The first duty of life is to live – to live as completely as possible – to increase life for oneself and for others, to make it more elevated, more sweet, and more beautiful.– Alexis Carrel

Prior to the 1900s, to sever a major central blood vessel meant certain death, and to injure an artery in an extremity would mean an amputation. However, Alexis Carrel, a French-born physician–scientist and controversial historical figure, developed successful vascular suturing techniques that dramatically shifted the odds of life and limb salvage. Carrel later pursued organ transplantation with the first successful animal renal transplant. In recognition of  “his  work  on vascular  sutures  and the transplantation of blood vessels and organs,” Alexis Carrel, in 1912, was the first scientist in America to be awarded the Nobel Prize for Medicine.

Singapore Med J 2013; 54(11): 602-603; http://dx.doi.org/doi:10.11622/smedj.2013217
http://smj.org.sg/sites/default/files/5411/5411ms1.pdf

REFERENCES

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• Durkin JT. Hope for Our Time: Alexis Carrel on Man and Society. New York: Harper & Row, 1965.
 
• Edwards WS, Edwards PD. Alexis Carrel: Visionary Surgeon. Illinois: Charles C Thomas, 1974.
 
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• Nobel Lectures: Physiology or Medicine 1901–1921. Amsterdam: Elsevier, 1967. Available at: http://nobelprize.org/nobel_prizes/medicine/laureates/1912/carrel-bio.html. Accessed 15 June 2008.
 
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