Eruptive syringoma in a patient with trisomy 21

Ong GCW, Lim KS, Chian LYT
Correspondence: Dr Gavin Chun Wei Ong, gavinong@nsc.gov.sg

ABSTRACT
Syringomas are benign adnexal neoplasia that are classified into four main types, according to their clinical features and associations. Syringoma associated with trisomy 21 typically presents with a periorbital cutaneous involvement. We report an 18-year-old Chinese girl with trisomy 21, who presented with eruptive syringoma, an unusual generalised form involving her trunk and limbs. A histological examination was performed to confirm the diagnosis.

Keywords: adenexal tumour, Down syndrome, eccrine tumour, eruptive syringoma, trisomy 21
Singapore Med J 2010; 51(2): e46-e47