Management of foetal hydrops secondary to Kell isoimmunisation via foetal blood transfusion: a Doppler-guided approach

Mohd J, Tan J, Yeo GSH
Correspondence: Dr Jasmine Mohd, jasmine.mohd@singhealth.com.sg

ABSTRACT
We describe a male neonate with foetal hydrops due to foetal anaemia caused by Kell isoimmunisation. The severity of anaemia was monitored by Doppler ultrasonography of the middle cerebral artery peak systolic velocity, and this was used to time the foetal blood transfusions. The 33-year-old Indian mother received a total of five foetal blood transfusions from 21 weeks to 31 weeks of gestation, resulting in resolution of the anaemia and hydrops.

Keywords: foetal anaemia, foetal blood transfusion, foetal hydrops, Kell isoimmunisation, middle cerebral artery peak systolic velocity
Singapore Med J 2009; 50(4): e143-e146